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Extra resources for Anatomy & Physiology Vocabulary - Study Notes
We will use a positional cloning strategy to test this hypothesis, identify the mutation responsible for DFNB17 and determine its putative functional and expression c characteristics. This project proposes to: 1) Refine and narrow the DFNB17 interval on chromosome 7q31. 2) Identify candidate cochlear expressed genes in the DFNB17 interval. 3) Identify the DFNB17 gene by determining the disease causing mutation in a family mapping the original locus and in novel families mapping to this interval.
Four specific aims will be addressed in this study: (1) design and test the effectiveness of an innovative intervention for OEs to increase their use of HPDs; (2) determine prevalence of hearing loss in OEs; (3) demonstrate the feasibility of providing computer-based self-administrated audiometric screening tests (SAAST) and hearing protection interventions at a construction worker training center; and (4) test and refine the Predictors of Use of Hearing Protection Model (PUHPM), a causal model designed to explain use of HPDs by OEs.
As the mouse ear is very similar to that of humans, we expect that our studies will apply to human ear development and shed light on the genetic mechanisms, which perturbs it, leading to hearing and balance disorders. ; Associate Professor; Communicative Disorders & Scis; State University of New York at Buffalo Suite 211 Ub Commons Buffalo, Ny 14228 Timing: Fiscal Year 2002; Project Start 15-SEP-2001; Project End 31-AUG-2004 Summary: (provided by applicant): Noise induced hearing loss has substantial impact on the productivity and quality of life for as many as 10 million people in the United States.
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